Equipoise is the brand name of the anabolic steroid boldenone. It is an oil-based injectable with an added undecylenate ester. Added ether helps increase half-life and release rate. The substance is a derivative of testosterone with symmetrical anabolic strength, but with reduced androgenic effects. Equipoise is a medicine used in veterinary medicine. But it has gained popularity among bodybuilders and athletes as a form of testosterone, a derivative with less estrogenic and androgenic activity. They like to compare Equipoise to Nandrolone (Deca-Durabolin), but it’s not the best comparison because Nandrolone has different properties and a completely different class of compounds (19-nor or progestin). But many believe that Equilibrium and Nandrolone are interchangeable drugs, even in anabolic steroid cycles.
As mentioned above, Equipoise is a synthetic testosterone derivative with a modified structure where double bonds between 1 and 2 carbons are added. This modification reduces Equipoise’s ability to interact with aromatase (the enzyme responsible for converting androgens to estrogens). As a result, Equipoise’s estrogenic activity is less than testosterone. The rest is boldenone with ether undecylenate attached to it. “Undecylenate” – Undecylenic acid interacts with boldenone to form a bond, which in chemistry is called an ester (ester bond). In the chemical structure of boldenone, undecylenic acid is attached to a 17-beta-hydroxyl group. The addition of this ester increases the rate of release of the hormone and its half-life. When boldenone undecylenate enters the bloodstream, enzymes in the body begin to break the bond between the ether and the hormone. The release of the main essential substance takes place at different rates, but as a result enzymes remove the ester, and pure boldenone remains in the body and performs its function freely. This fermentation process with the release of the ester hormone slows down the release rate of the main active ingredient. In summary, undecylenate together with boldenone increases its half-life by 14 days. Thus, without an ester, the hormone does not provide sufficiently slow release and the necessary activity.
As mentioned at the beginning of this section, Equipoise and Dianabol are structurally identical. The only difference between the two is that Equipoise contains the undecylenate ester attached to its 17beta hydroxyl group while Dianabol contains a methyl group attached to its 17beta hydroxyl group. Dianabol’s methyl group (aka C17-alpha-alkylation) when taken orally prevents it from being metabolised and broken down by the liver. Apart from this difference, these two hormones are completely identical and are considered to be the same compound below. But when they enter the body, Equipoise and Dianabol manifest themselves in different ways. This is very convincing evidence that the addition of a methyl group (C17 alpha-alkylation) to carbon 17 not only affects the hormone’s resistance to hepatic degradation, but also alters the action and properties of the anabolic steroid set.
Because Equipoise is derived from testosterone, this offers many symmetrical properties. First, it has exactly the same degree of anabolic strength (index 100). Second, Equipoise is an aromatizable anabolic steroid and can be converted to estrogen by interacting in the body with the aromatase enzyme. The modification with a double bond between carbon atoms 1 and 2 reduces its ability to aromatize and therefore provides a lower estrogenic activity of the balance in the body.
All of this means that equipoise converts to estrogen, but in much lower amounts than its parent hormone, testosterone. This positive property does not exclude the occurrence of estrogenic side effects, which should be taken into account when taking the drug. Therefore, do not rely on Equipoise not retaining water in the body. This will only happen to a relatively small extent. Of course, everything is individual and depends on the body’s sensitivity to the drug. However, in moderate doses, Equipoise should not cause fluid retention in the body or other adverse manifestations.